Camelot notation is a way of renaming the 24 keys so that harmonic relationships become arithmetic. Each key gets a number from 1 to 12 and a letter: A for minor, B for major. A minor is 8A; C major, which shares the same notes, is 8B.
Arranged that way, keys next to each other on the wheel differ by a single note. So from 8A you can move to 7A, 9A or 8B and expect the transition to sit comfortably. Moving several steps at once, or jumping between distant numbers, is where clashes come from — which is exactly the problem the wheel was invented to make visible.
The same logic applies outside DJing. If you are layering a sample over your own track, picking a loop from a pack, or deciding which of your demos belong in the same body of work, adjacent Camelot codes are the ones that will need the least transposing.